Case Study Analysis

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Case Study Analysis

Slowly progressive Parkinson's Disease (PD) is characterized by resting tremor, rigidity, slowness, and reduced mobility and walking capacity (bradykinesia) and is common in advanced stages. She made the diagnosis. Treatment aims to improve dopamine production in the brain using levodopa or other dopaminergic medication. Patients without a diagnosed or suspected dementia are not candidates for neurosurgery. Might benefit from stereotactic or ablative deep brain stimulation treatments (Parkinson's Foundation, nd)

Physiologic pathology

Synuclein is found in the neurons and the oligodendoplasmic inclusions associated with glial cells to form Lewy bodies. Parkinson's disease pathology is characterized by the presence of Lewy bodies in the substantial nigrostriatal pathway plexus. But also tends to concentrate in the dorsal vagal motor nucleus, the Meynert basal nucleus, the hypothalamus, the neocortex, and the sympathetic ganglia. Lewy bodies appear gradually, and experts suspect that it occurs at a late stage of Parkinson's syndrome. These diseases, often known as Lewy body disease, include subtypes of Parkinson's Disease, diffuse Lewy body disease, and multi-system atrophy. Autonomic instability and dementia are characteristics of Parkinson's Disease, however (Holland 2019)

Parkinson's Disease develops relatively infrequently in the absence of Lewy bodies, for example, in...